Duque will be responsible for 24 experiments in total. Most of them will be performed in the Russian part of the ISS. Some experiments will be done in NASA’s Destiny laboratory. Destiny will host, for example, all physical science experiments to be developed in the Microgravity Science Glovebox, an ESA facility to work in a fully sterilised environment.
Most of the experiments are sponsored by the Spanish government, although there are also a number of reflights of experiments from the Belgian Odissea mission to the ISS in October 2002.
Duque will be responsible for the following experiments: